English (United Kingdom)

https://curated-unify.zendy.io/wp-json/zendy-region/v1/featured_content/oa?rat=en

https://curated-unify.zendy.io/wp-json/zendy-region/v1/highlighted_journal/

Global: Zendy Tools annual

Presents the keyphrase highlighting as premium feature

Keyphrase Highlighting

Presents the summarisation as premium feature

Summarisation

Insights

Presents the pdf analysis as premium feature

PDF Analysis

Presents the zaia usage as premium feature

ZAIA

Global: Zendy Tools monthly

Global: Zendy Plus monthly

Presents the access of premium content as premium feature

Premium Content

Global: Zendy Plus annual

Global: Zendy Free Plan

Background and Aim . Risk factors for  Helicobacter pylori  infection are genetic susceptibility and poor living conditions. This study aimed to investigate the  Mdm2  gene, clarithromycin resistance, and possible risk factors for  Helicobacter pylori  infection.  Methods . Risk factors and clinical characteristics were analyzed, including patient demographic data, patient income, personal history, possible source of transmission, patient symptoms, endoscopic findings, patterns of clarithromycin resistance, and patterns of  Mdm2  SNIP309.  Results . Ingestion of pickled fish (OR = 11.27, 95% CI = 4.31–29.45,  p  < 0.0001), salt crab (OR = 8.83, 95% CI = 1.99–39.14,  p  < 0.001), and Papaya salad (OR = 8.73, 95% CI = 4.54–16.79,  p  < 0.01). The prevalence of clarithromycin resistance was 56% (wild type, A2143/2142A, is 23.8%; mutation, A2143/2142CG, is 35.7%; wild type + mutation is 40.5%). The genetic polymorphisms of  Mdm2  SNIP309 were SNIP309 T/T homozygous in 78%, SNIP309 G/T heterozygous in 19%, and SNIP309 G/G homozygous in 3%.  Conclusion . Pickled fish, salt crab, and Papaya salad are positive risk factors. There was high prevalence of clarithromycin resistance. The  Mdm2  SNIP309 G/G homozygous genotype might be a risk factor for gastric cancer and the fact that it is infrequent in Thailand.

Characteristics and Risk Factors ofHelicobacter pyloriAssociated Gastritis: A Prospective Cross-Sectional Study in Northeast Thailand