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Background . Synthetic cathinones (SCs), also known as “bath salts,” are  β -ketone amphetamine compounds derived from cathinone, a psychoactive substance found in  Catha edulis . Mephedrone is the most representative SC.  Slamming  is the term used for the intravenous injection of these substances in the context of  chemsex  parties, in order to enhance sex experiences. Using IV mephedrone may lead to diverse medical and psychiatric complications like psychosis, aggressive behavior, and suicide ideation.  Case . We report the case of a 25-year-old man admitted into a psychiatric unit, presenting with psychotic symptoms after  slamming  mephedrone almost every weekend for the last 4 months. He presents paranoid delusions, intense anxiety, and visual and kinesthetic hallucinations. He also shows intense craving, compulsive drug use, general malaise, and weakness. After four weeks of admission and antipsychotic treatment, delusions completely disappear. The patient is reinfected with hepatitis C.  Discussion . Psychiatric and medical conditions related to  chemsex  and  slamming  have been reported in several European cities, but not in Spain. Psychotic symptoms have been associated with mephedrone and other SCs' consumption, with the IV route being prone to produce more severe symptomatology and addictive conducts. In the case we report, paranoid psychosis, addiction, and medical complications are described.

Severe Psychosis, Drug Dependence, and Hepatitis C Related toSlammingMephedrone