English (United Kingdom)

https://curated-unify.zendy.io/wp-json/zendy-region/v1/featured_content/oa?rat=en

https://curated-unify.zendy.io/wp-json/zendy-region/v1/highlighted_journal/

Global: Zendy Plus annual

Presents the access of premium content as premium feature

Premium Content

Presents the keyphrase highlighting as premium feature

Keyphrase Highlighting

Presents the summarisation as premium feature

Summarisation

Insights

Presents the pdf analysis as premium feature

PDF Analysis

Presents the zaia usage as premium feature

ZAIA

Global: Zendy Tools annual

Global: Zendy Free Plan

Global: Zendy Tools monthly

Global: Zendy Plus monthly

Tissue engineering is a multidisciplinary science based on the application of engineering approaches to biologic tissue formation.\udEngineered tissue internal organization represents a key aspect to increase biofunctionality before transplant and, as regarding\udskeletal muscles, the potential of generating contractile forces is dependent on the internal fiber organization and is reflected by\udsome macroscopic parameters, such as the spontaneous contraction. Here we propose the application of digital image correlation\ud(DIC) as an independent tool for an accurate and noninvasive measurement of engineered muscle tissue spontaneous contraction.\udTo validate the proposed technique we referred to the X-MET, a promising 3-dimensional model of skeletal muscle. The images\udacquired through a high speed camera were correlated with a custom-made algorithm and the longitudinal strain predictions were\udemployed for measuring the spontaneous contraction. The spontaneous contraction reference values were obtained by studying\udthe force response.The relative error between the spontaneous contraction frequencies computed in both ways was always lower\udthan 0.15%. In conclusion, the use of a DIC based systemallows for an accurate and noninvasive measurement of biological tissues’\udspontaneous contraction, in addition to the measurement of tissue strain field on any desired region of interest during electrical\udstimulation

A DIC Based Technique to Measure the Contraction of a Skeletal Muscle Engineered Tissue