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In this study, the authors have developed endoscopic fibre-optic pressure sensor to detect variceal pressure and presented the validation of  in vivo  and  in vitro  studies, because the HVPG requires catheterization of hepatic veins, which is invasive and inconvenient. Compared with HVPG, it is better to measure directly the variceal pressure without puncturing the varices in a noninvasive way.

Validation of an Endoscopic Fibre-Optic Pressure Sensor for Noninvasive Measurement of Variceal Pressure