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Aim . To compare the efficacy of using computed tomography enteroclysis/enterography (CTE), capsule endoscopy (CE), and CTE with CE for diagnosing tumor lesions in the small intestine.  Materials and Methods . We included 98 patients who underwent CE during the observation period and were subjected to CTE at our hospital from April 2008 to May 2014.  Results . CTE had a significantly higher sensitivity than CE (84.6% versus 46.2%,  P  = 0.039), but there were no significant differences in specificity, positive or negative predictive values, or diagnostic accuracy rates. The sensitivity of CTE/CE was 100%, again significantly higher than that of CE ( P  = 0.002). The difference in specificity between CTE/CE and CE was not significant, but there were significant differences in positive predictive values (100% for CTE/CE versus 66.7% for CE,  P  = 0.012), negative predictive values (100% versus 92.1%,  P  = 0.008), and diagnostic accuracy rate (100% versus 89.8%,  P  = 0.001). The diagnostic accuracy rate was also significantly higher in CTE/CE versus CTE (100% versus 95.9%,  P  = 0.043).  Conclusion . Our findings suggested that a combination of CTE and CE was useful for screening tumor lesions in the small intestine. This trial is registered with number  UMIN000016154 .

gastroenterology research and practice

Beneficial Effects of Combining Computed Tomography Enteroclysis/Enterography with Capsule Endoscopy for Screening Tumor Lesions in the Small Intestine