English (United Kingdom)

https://curated-unify.zendy.io/wp-json/zendy-region/v1/featured_content/oa?rat=en

https://curated-unify.zendy.io/wp-json/zendy-region/v1/highlighted_journal/

Global: Zendy Plus annual

Presents the access of premium content as premium feature

Premium Content

Presents the keyphrase highlighting as premium feature

Keyphrase Highlighting

Presents the summarisation as premium feature

Summarisation

Insights

Presents the pdf analysis as premium feature

PDF Analysis

Presents the zaia usage as premium feature

ZAIA

Global: Zendy Tools annual

Global: Zendy Free Plan

Global: Zendy Tools monthly

Global: Zendy Plus monthly

The essential oils (EO) and bioactive fractions (BF) from  Aloysia gratissima, Baccharis dracunculifolia, Coriandrum sativum, Cyperus articulatus,  and  Lippia sidoides  were proven to have strong antimicrobial activity on planktonic microorganisms; however, little is known about their effects on the morphology or viability of oral biofilms. Previously, we determined the EO/fractions with the best antimicrobial activity against  Streptococcus mutans  and  Candida  spp. In this report, we used a confocal analysis to investigate the effect of these EO and BF on the morphology of  S. mutans  biofilms (thickness, biovolume, and architecture) and on the metabolic viability of  C. albicans  biofilms. The analysis of intact treated  S. mutans  biofilms showed no statistical difference for thickness in all groups compared to the control. However, a significant reduction in the biovolume of extracellular polysaccharides and bacteria was observed for  A. gratissima  and  L. sidoides  groups, indicating that these BF disrupt biofilm integrity and may have created porosity in the biofilm. This phenomenon could potentially result in a weakened structure and affect biofilm dynamics. Finally,  C. sativum  EO drastically affected  C. albicans  viability when compared to the control. These results highlight the promising antimicrobial activity of these plant species and support future translational research on the treatment of dental caries and oral candidiasis.

The Effect of Essential Oils and Bioactive Fractions onStreptococcus mutansandCandida albicansBiofilms: A Confocal Analysis