English (United Kingdom)

https://curated-unify.zendy.io/wp-json/zendy-region/v1/featured_content/oa?rat=en

https://curated-unify.zendy.io/wp-json/zendy-region/v1/highlighted_journal/

Global: Zendy Tools annual

Presents the keyphrase highlighting as premium feature

Keyphrase Highlighting

Presents the summarisation as premium feature

Summarisation

Insights

Presents the pdf analysis as premium feature

PDF Analysis

Presents the zaia usage as premium feature

ZAIA

Global: Zendy Tools monthly

Global: Zendy Plus monthly

Presents the access of premium content as premium feature

Premium Content

Global: Zendy Plus annual

Global: Zendy Free Plan

Natural resistance-associated macrophage protein (Nramp1) and the vitamin D receptor (VDR) are central components of the innate and adaptive immunity against  Mycobacterium tuberculosis , and associations between susceptibility to tuberculosis and polymorphisms in the genes  NRAMP  and  VDR  have been sought in geographically diverse populations. We investigated associations of  NRAMP1  and  VDR  gene polymorphisms with susceptibility to TB in the Venezuelan population. The results suggest the absence of any association between  VDR  variants  FokI, ApaI , and  TaqI  and susceptibility to tuberculosis. In contrast, the  NRAMP1 3′UTR  variants were associated with susceptibility to  M. tuberculosis  infection, as seen in the comparisons between TST+ and TST− controls, and also with progression to TB disease, as shown in the comparisons between TB patients and TST+ controls. This study confirms the previously described association of the  NRAMP1 3′UTR  polymorphism with  M. tuberculosis  infection and disease progression.

NRAMP1andVDRGene Polymorphisms in Susceptibility to Tuberculosis in Venezuelan Population