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The mosquito  Aedes aegypti  L. (Diptera: Culicidae) is the major vector of dengue and chikungunya fever. The lack of effective therapies and vaccines for these diseases highlights the need for alternative strategies to control the spread of virus. Therefore, this study investigated the larvicidal potential of essential oils from common plant species obtained from the Chapada das Mesas National Park, Brazil, against third instar  A. aegypti  larvae. The chemical composition of these oils was determined by gas chromatography coupled to mass spectrometry. The essential oils of  Eugenia piauhiensis  Vellaff.,  Myrcia erythroxylon  O. Berg,  Psidium myrsinites  DC., and  Siparuna camporum  (Tul.) A. DC. were observed to be mainly composed of sesquiterpene hydrocarbons. The essential oil of  Lippia gracilis  Schauer was composed of oxygenated monoterpenes. Four of the five tested oils were effective against the  A. aegypti  larvae, with the lethal concentration (LC 50 ) ranging from 230 to 292 mg/L after 24 h of exposure. Overall, this work demonstrated the possibility of developing larvicidal products against  A. aegypti  by using essential oils from the flora of the Brazilian Legal Amazon. This in turn demonstrates the potential of using natural resources for the control of disease vectors.

evidence-based complementary and alternative medicine

Chemical Composition and Larvicidal Activity of Essential Oils Extracted from Brazilian Legal Amazon Plants against<i>Aedes aegypti</i>L. (Diptera: Culicidae)

Chemical Composition and Larvicidal Activity of Essential Oils Extracted from Brazilian Legal Amazon Plants againstAedes aegyptiL. (Diptera: Culicidae)