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The pharmacological evaluation demonstrated that the extracts from the stem of  S. brachyanthera  could significantly increase the outputs of urine of rats compared to those of furosemide treated group, and the effect could last for a longer period of time. The best effect appeared in the first two hours, which scientifically confirmed the diuretic effect of the plant. The comparative pharmacognosy study showed that the characters of the crude drugs of the stem of  S. brachyanthera  were similar to those of  Akebia caulis . Further systemic work on its chemical constituents by chromatographic methods and NMR elucidations led to the isolation of 10 triterpenoids, 6 flavonoids, 4 lignanoids, and 3 phenylethanoid glycosides, whose structural types were much similar to those of  A. quinata . Among them, 7 compounds were firstly reported in the genus of  Stauntonia  and calceolarioside B was the common characteristic constituent in both plants. From the similar pharmacognosy characters, pharmacological effects, and chemical constituents, it could be concluded that  S. brachyanthera  have a great possibility to be a succedaneum of  Akebia caulis , whose supply is extremely short in recent years.

Diuretic Properties and Chemical Constituent Studies onStauntonia brachyanthera