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Objectives . To investigate changes in pulsograph caused by pain in primary dysmenorrhea (PD) patients.  Methods . Pulsograph and pain level of PD patients were detected using electropulsograph and Visual-Analogue Scale (VAS), respectively, at four time points, 7–10 days before menstruation ( T 0), maximal pain during menstruation ( T 1), immediately after acupuncture analgesia ( T 2), and 30 mins after acupuncture analgesia ( T 3). Parameters ( t ,  h ,  w ) and normalized time parameters ( t ′) of pulsograph were analyzed.  Results . VAS pain scores decreased from 6.40 ± 1.13 at  T 1 to 0.70 ± 0.75 at  T 2 to 0.11 ± 0.32 at  T 3 ( P  < 0.001 and 0.001). At  T 1, compared with those at  T 0,  w 1,  h 3, and  h 4 significantly increased ( P  < 0.01), and  t 2,  t 2′,  t 3′, and  h (d) significantly decreased ( P  < 0.01, 0.001, 0.05, and 0.001). At  T 2, compared with those at  T 1,  t 1,  w 1,  w 2,  h 2,  h 3,  t 1′, and  t 4′ significantly decreased ( P  < 0.05, 0.01, 0.01, 0.001, 0.01, 0.001, and 0.05), and  h (d) significantly increased ( P  < 0.001). There was no difference between  T 2 and  T 3.  Conclusions . There are almost opposite changing trends in pulsographic parameters when pain occurs and when it is relieved in PD patients.

Pain-Induced Pulsograph Changes in Patients with Primary Dysmenorrhea: A Pilot Study