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Objectives . To retrospectively compare the results of the MRIA (magnetic resonance index of activity) with a modified MRIA (mMRIA), which was calculated excluding from MRIA formula the data of relative contrast enhancement (RCE).  Materials and Methods . MR-E and corresponding endoscopic records of 100 patients were reviewed. MRIA, mMRIA, and SES endoscopic index were calculated for all the patients. Namely, MRIA was calculated as follows: (1.5 × wall thickening + 0.02 × RCE + 5 × intramural edema + 10 × ulcers), while mMRIA was calculated with the modified formula (1.5 × wall thickening + 5 × intramural edema + 10 × ulcers).  Results . Mean MRIA and mMRIA values were 19.3 and 17.68, respectively ( p  < 0.0001). A significant correlation ( p  < 0.0001) was observed between MRIA and mMRIA scores and between both MR indexes and SES ( p  < 0.0001).  Conclusions . mMRIA was comparable to MRIA in the evaluation of disease activity in Crohn's disease.

gastroenterology research and practice

Assessment of Disease Activity in Small Bowel Crohn’s Disease: Comparison between Endoscopy and Magnetic Resonance Enterography Using MRIA and Modified MRIA Score