English (United Kingdom)

https://curated-unify.zendy.io/wp-json/zendy-region/v1/featured_content/oa?rat=en

https://curated-unify.zendy.io/wp-json/zendy-region/v1/highlighted_journal/

Global: Zendy Plus annual

Presents the access of premium content as premium feature

Premium Content

Presents the keyphrase highlighting as premium feature

Keyphrase Highlighting

Presents the summarisation as premium feature

Summarisation

Insights

Presents the pdf analysis as premium feature

PDF Analysis

Presents the zaia usage as premium feature

ZAIA

Global: Zendy Plus monthly

Global: Zendy Tools annual

Global: Zendy Tools monthly

Global: Zendy Free Plan

Human cystic echinococcosis remains a major public health problem on several countries and the treatment strategies are not solved. The aim of the present work was to determine the in vitro effect of thymol and  Mentha piperita ,  M. pulegium,  and  Rosmarinus officinalis  essential oils on the proliferation of  E. granulosus  larval cells. Isolated cells and cellular aggregates were obtained from hydatid cyst's germinal layer and exposed to 1, 5, and 10  μ g/ml of thymol and the different essential oils for 7 days. Drug effect was evaluated using test viability and scanning electron microscopy. Control cell culture viability was 2.1 x 10 6  (100%) after 7 days of incubation. At day 7, thymol 5  μ g/ml caused a reduction in cell viability of 63% and the essential oils of  M. piperita  10  μ g/ml,  M. pulegium  10  μ g/ml, and  R. officinalis  10  μ g/ml produced a reduction in the viability of 77, 82, and 71%, respectively. Moreover essential oils caused reduction in cell number, collapsed cells, and loss of normal tridimensional composition of the aggregates. Due to the inhibitory effect caused by essential oils on  E. granulosus  cells we suggested that it would be an effective means for suppression of larval growth.

Effect of Different Terpene-Containing Essential Oils on the Proliferation ofEchinococcus granulosusLarval Cells