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Background and Objectives . Skeletal muscle and skeletal muscle indices in young adults from developing countries are sparse. Indices and the corresponding cut-off points can be a reference for diagnoses of sarcopenia. This study assessed skeletal muscle using dual-energy X-ray absorptiometry (DXA) in healthy male and female subjects aged 20–40 years and compared their appendicular skeletal muscle mass (ASM) and total-body skeletal muscle (TBSM) indices using certain cut-off points published in the literature.  Methods . A sample of 216 healthy adults men and women from northwest Mexico was included. Body composition was assessed by DXA and several published DXA-derived skeletal muscle indices were compared.  Results . Both, ASM and TBSM were higher in men compared to the women group (23.0 ± 3.4 versus 15.9 ± 1.6 kg;  P  < 0.05 and 26.5 ± 4.1 versus 16.9 ± 1.9 kg;  P  < 0.05, resp.). These differences were also valid for both indices. When derived cut-off points were compared with the most reported indices, significant differences were found.  Interpretation and Conclusion . Published cut-off points from Caucasians are higher than cut-off point derived in this sample of Mexican subjects. The new DXA-derived cut-off points for ASM proposed herein may improve diagnoses of sarcopenia in the geriatric Mexican population.

Skeletal Muscle Mass Indices in Healthy Young Mexican Adults Aged 20–40 Years: Implications for Diagnoses of Sarcopenia in the Elderly Population