English (United Kingdom)

https://curated-unify.zendy.io/wp-json/zendy-region/v1/featured_content/oa?rat=en

https://curated-unify.zendy.io/wp-json/zendy-region/v1/highlighted_journal/

Global: Zendy Plus annual

Presents the access of premium content as premium feature

Premium Content

Presents the keyphrase highlighting as premium feature

Keyphrase Highlighting

Presents the summarisation as premium feature

Summarisation

Insights

Presents the pdf analysis as premium feature

PDF Analysis

Presents the zaia usage as premium feature

ZAIA

Global: Zendy Tools annual

Global: Zendy Free Plan

Global: Zendy Tools monthly

Global: Zendy Plus monthly

The biological activities of the branch bark ethanol extract (BBEE) in the mulberry  Morus alba  L. were investigated. The determination of active component showed that the flavonoids, phenols, and saccharides are the major components of the ethanol extract. The BBEE had a good scavenging activity of the 1,1-diphenyl-2-picrylhydrazyl (DPPH) radical with around 100   μ  g/mL of IC 50  value.  In vitro  assay revealed that the BBEE strongly inhibited both   α  -glucosidase and sucrase activities whose IC 50  values were 8.0 and 0.24   μ  g/mL, respectively. The kinetic analysis showed that the BBEE as a kind of   α  -glucosidase inhibitor characterized a competitive inhibition activity. Furthermore, the carbohydrate tolerance of the normal mice was obviously enhanced at 0.5 h ( P  < 0.05) and 1.0 h ( P  < 0.05) after the BBEE intragastric administration as compared to negative control. At 0.5, 1.0, 1.5, and 2.0 h after the intragastric administration with starch, the postprandial hyperglycemia of the type 2 diabetic mice can be significantly decreased ( P  < 0.01) by supplying various concentrations of the BBEE (10–40 mg/kg body weight). Therefore, the BBEE could effectively inhibit the postprandial hyperglycemia as a novel   α  -glucosidase activity inhibitor for the diabetic therapy.

Preparation of the Branch Bark Ethanol Extract in MulberryMorus alba, Its Antioxidation, and Antihyperglycemic ActivityIn Vivo