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Elephantopus scaber  is an ethnomedicinal plant used by the Zhuang people in Southwest China to treat headaches, colds, diarrhea, hepatitis, and bronchitis. A new   δ  -truxinate derivative, ethyl, methyl 3,4,3′,4′-tetrahydroxy-  δ  -truxinate ( 1 ), was isolated from the ethyl acetate extract of the entire plant, along with 4 known compounds. The antioxidant activity of these 5 compounds was determined by ABTS radical scavenging assay. Compound  1  was also tested for its cytotoxicity effect against HepG2 by MTT assay (IC 50  = 60   μ  M), and its potential anti-inflammatory, antibiotic, and antitumor bioactivities were predicted using target fishing method software.

Bioactivities of Compounds fromElephantopus scaber, an Ethnomedicinal Plant from Southwest China