Synthesis, Characterization, and Antimicrobial Activity of Methyl‐2‐aminopyridine‐4‐carboxylate Derivatives
Author(s) -
S. Nagashree,
P. Mallu,
L. Mallesha,
S. Bindya
Publication year - 2012
Publication title -
journal of chemistry
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.436
H-Index - 50
eISSN - 2090-9071
pISSN - 2090-9063
DOI - 10.1155/2013/312961
Subject(s) - chemistry , antimicrobial , 2 aminopyridine , carboxylate , elemental analysis , in vitro , organic chemistry , proton nmr , stereochemistry , biochemistry
A series of methyl-2-aminopyridine-4-carboxylate derivatives, 3a–f, were synthesized in order to determine their in vitro antimicrobial activity. The chemical structures of the synthesized compounds were confirmed by elemental analyses, FT-IR, and 1H NMR spectral studies. Among the synthesized compounds, 3c and 3d showed good antimicrobial activity compared to other compounds in the series
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