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During anti- Malassezia  screening of plants by CLSI broth microdilution method,  Cladia aggregata  (Swartz) Nyl. (family Cladoniaceae), a fruticose lichen from Sikkim (northeast Himalayan region), has been found effective at minimum inhibitory concentrations (mg/mL) of 2.72, 0.63, and 1.28 against yeast-like fungi namely,  M. furfur, M. globosa  and  M. sympodialis,  respectively. These test pathogens are responsible for pityriasis versicolor (PV) and seborrheic dermatitis (SD) in humans. We tried to establish the reason for variable MICs against various  Malassezia  spp. using bioinformatical tools, thereby reducing the cost of the experimentation. This is the first report on anti- Malassezia  activity of  C. aggregata  and thus can serve as a potential source for the development of cosmaceuticals.

Management of Cosmetic Embarrassment Caused byMalasseziaspp. with Fruticose LichenCladiaUsing Phylogenetic Approach