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Protective immunity against mycobacterial infections such as  Mycobacterium tuberculosis  is mediated by interactions between specific T cells and activated antigen presenting cells. To date, many aspects of mycobacterial immunity have shown that innate cells could be the key elements that substantially may influence the subsequent adaptive host response. During the early phases of infection, innate lymphocyte subsets play a pivotal role in this context. Here we summarize the findings of recent investigations on   γδ   T lymphocytes and their role in tuberculosis immunity.

γδT Cells Cross-Link Innate and Adaptive Immunity inMycobacterium tuberculosisInfection