English (United Kingdom)

https://curated-unify.zendy.io/wp-json/zendy-region/v1/featured_content/oa?rat=en

https://curated-unify.zendy.io/wp-json/zendy-region/v1/highlighted_journal/

Global: Zendy Plus annual

Presents the access of premium content as premium feature

Premium Content

Presents the keyphrase highlighting as premium feature

Keyphrase Highlighting

Presents the summarisation as premium feature

Summarisation

Insights

Presents the pdf analysis as premium feature

PDF Analysis

Presents the zaia usage as premium feature

ZAIA

Global: Zendy Plus monthly

Global: Zendy Tools annual

Global: Zendy Tools monthly

Global: Zendy Free Plan

The azoospermia factor (AZF) regions consist of three genetic domains in the long arm of the human Y chromosome referred toas AZFa, AZFb and AZFc. These are of importance for male fertility since they are home to genes required for spermatogenesis.In this paper a comprehensive analysis of AZF structure and gene content will be undertaken. Particular care will be given tothe molecular mechanisms underlying the spermatogenic impairment phenotypes associated to AZF deletions. Analysis of the 14different AZF genes or gene families argues for the existence of functional asymmetries between the determinants; while some areprominent players in spermatogenesis, others seem to modulate more subtly the program. In this regard, evidence supporting thenotion that DDX3Y, KDM5D, RBMY1A1, DAZ, and CDY represent key AZF spermatogenic determinants will be discussed

Genetic Dissection of the AZF Regions of the Human Y Chromosome: Thriller or Filler for Male (In)fertility?