English (United Kingdom)

https://curated-unify.zendy.io/wp-json/zendy-region/v1/featured_content/oa?rat=en

https://curated-unify.zendy.io/wp-json/zendy-region/v1/highlighted_journal/

Global: Zendy Plus annual

Presents the access of premium content as premium feature

Premium Content

Presents the keyphrase highlighting as premium feature

Keyphrase Highlighting

Presents the summarisation as premium feature

Summarisation

Insights

Presents the pdf analysis as premium feature

PDF Analysis

Presents the zaia usage as premium feature

ZAIA

Global: Zendy Tools annual

Global: Zendy Free Plan

Global: Zendy Tools monthly

Global: Zendy Plus monthly

High steroid doses are often necessary in congenital adrenal hyperplasia (CAH) to suppress androgens and may increase blood pressure (BP). We evaluated 24-hour BP profile (ambBP), BP during exercise (excBP), and echocardiography in 20 young CAH patients. Systolic and diastolic BP during ambBP and excBP was normal in all patients. None presented myocardial hypertrophy. Nocturnal diastolic BP was affected by testosterone (P: .016, 95&#37; CI: 0.002 to 0.021, &#x03B2; = 0.01). Left ventricular mass (LVM ) was affected by height SDS (P: .007, 95&#37; CI: 2.67 to 14.17, &#x03B2; = 8.42), age (P: &#x003C;.0001, 95&#37; CI: 2.12 to 5.82, &#x03B2; = 3.97), and testosterone (P: .008, 95&#37; CI: 0.01 to 0.09, &#x03B2; = 0.053). Left ventricular mass index (LVMI) correlated with BMI SDS (P: .044, 95&#37; CI: 0.09 to 6.17, &#x03B2; = 3.13) and testosterone (P: .031, 95&#37; CI: 0.002 to 0.035, &#x03B2; = 0.018). Hydrocortisone dose did not influence ambBP, excBP, or myocardial hypertrophy

Blood Pressure and Left Ventricular Characteristics in Young Patients with Classical Congenital Adrenal Hyperplasia due to 21-Hydroxylase Deficiency