Nickel(II) Complexes of Hydrazone of Isoniazid and Their Magneto‐Spectral, Electrochemical, Thermal and Antimicrobial Investigations

The synthesis of novel nickel(II) complexes with new ligand derived from hydrazone of isoniazid has been reported. The complexes have general compositions [Ni(L)2X2] or [Ni(L)3](ClO4)2, where L = N-isonicotinamido-furfuraldimine (INH-FFL) and X=Cl− or NCS−. The ligand hydrazone behaves as neutral bidentate (N and O donor) through the carbonyl oxygen and azomethine nitrogen. On the basis of elemental analysis, molecular weight determinations, magnetic susceptibility/moment, thermogravimetric, electrochemical, and spectroscopic studies, the new complexes have been characterized with octahedral geometry. The antibacterial and antifungal studies of the present complexes show that they are moderate antibacterial and antifungal agents