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CeF3:Tb3+ nanoparticles were successfully prepared by a polyol process using diethylene glycol (DEG) as solvent. After being coated with dense silica, these CeF3:Tb3+ nanoparticles can be coated with mesoporous silica using nonionic triblock copolymer EO20PO70EO20 (P 123) as structure-directing agent. The composite can load ibuprofen and release the drug in the PBS. The composite was characterized by X-ray diffraction (XRD), transmission electron microscopy (TEM), nitrogen absorption/desorption isotherms, fluorescence spectra, and UV/Vis absorption spectra, respectively. The composite particles have considerable large pore volume and large surface area. In addition, the composite still emits strong green fluorescence (Tb3+) and can be used as fluorescent probes in drug delivery system

journal of nanomaterials

Mesoporous Silica Coated<mml:math xmlns:mml="http://www.w3.org/1998/Math/MathML" id="E1"><mml:mrow><mml:msub><mml:mrow><mml:mtext>CeF</mml:mtext></mml:mrow><mml:mtext mathvariant="bold">3</mml:mtext></mml:msub></mml:mrow></mml:math>:<mml:math xmlns:mml="http://www.w3.org/1998/Math/MathML" id="E2"><mml:mrow><mml:msup><mml:mrow><mml:mtext>Tb</mml:mtext></mml:mrow><mml:mrow><mml:mtext mathvariant="bold">3+</mml:mtext></mml:mrow></mml:msup></mml:mrow></mml:math>Particles for Drug Release

Mesoporous Silica CoatedCeF3:Tb3+Particles for Drug Release