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ln order to evaluate the association between Camphlobacter pyloriand gastritis, two biopsies were taken from the duodenal bulb, antrum, body andfundus (and from lesions if there were any) in 100 consecutive patients referred to thisgastroscopic clinic For each site, one biopsy was for histology and C pylon detection byWarthin-Starry staining, and the second biopsy was for culture. In addition, for eachpatient a gastric brushing was Gram stained. Twenty-one patients were excludedfrom the study. Among the remaining, 13 patients had positive biopsy culture for Cpylori and, of these, 30 (91%) had gastritis (including 23 with active chronic gastritis).This culture sensitivity increased with the number of biopsies. Forty-two patientshad a positive brushing specimen, of which 30 (71%) had gastritis. Gram stain on abrushing specimen had a sensitivity of 84.8%, in comparison with the biopsy culture.Of the 23 patients with positive Warthin-Starry stain , 19(83%) had an histology ofgastritis. There was a strong correlation between the presence of C pylori in the stomachmucosa and the gastritis. The incidence of C pylori associated gastritis is similar inQuebec to other parts of the world. The biopsy culture is a simple and specific test,and at least two biopsies are necessary for a good sensitivity. Gram stain on a brushingspecimen is an adequate test for rapid detection of C pylori in the stomach

Campylobacter pyloriDetection in Gastric Mucosa: Association with Gastritis