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Autoimmune chronic active hepatitis (CAH) and primary sclerosingcholangitis (PSC) arc chronic diseases of the hepatobiliary system that have manyclinical, immunologic and genetic features in common. Despite these similarities, thereare few reports of the two diseases coexisting. Two young women with clinical, biochemical,serologic, radiologic and histologic findings compatible with both autoimmuneCAH and PSC are described. The observation that there may be a strikingoverlap in the features of these two diseases and recent improvements in diagnosticimaging of the biliary tract suggest that the association of these two diseases in the sameindividual may be more common than is presently appreciated

Autoimmune Chronic Active Hepatitis (Lupoid Hepatitis) and Primary Sclerosing Cholangitis in Two Young Adult Females