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the v-atpase is a large (∼900 kDa) multisubunit enzyme that utilizes energy derived from hydrolysis of ATP to translocate H+ across biological membranes. In the kidney, apical V-ATPase regulates H+ secretion into the urine and there is evidence for its existence in the proximal tubule, thick

Connecting type A intercalated cell metabolic state to V-ATPase function: phosphorylation does matter!