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macrophages are a group of fascinating immune cells that play a critical role in mediating kidney injury, repair, and fibrosis ([9][1]). The vast majority, if not all, of the macrophages originate from myeloid precursors in the bone marrow and are released into circulation as monocytes ([10][2]).

Macrophage-derived TGF-β in renal fibrosis: not a macro-impact after all