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To quantitatively characterize early emphysematous changes in the lung microstructure of current and former smokers with noninvasive helium 3 ((3)He) lung morphometry and to compare these results with the clinical standards, pulmonary function testing (PFT) and low-dose computed tomography (CT).

In Vivo Detection of Acinar Microstructural Changes in Early Emphysema with3He Lung Morphometry

In Vivo Detection of Acinar Microstructural Changes in Early Emphysema with³He Lung Morphometry