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Ultrasound imaging was used to investigate vastus medialis (VM) architecture in 10 males and 10 females at different knee angles. Increase in muscle thickness occurs predominantly when the knee angle is changed from 0° (full extension) and 45° (p &lt; 0.05); increases in VM pennation angle can be predominantly observed between 45° and 90° (p &lt; 0.05). Sex differences in the VM architecture can be observed in the distal (p &lt; 0.01) but not in the proximal region of the muscle (p &gt; 0.11).

Influence of knee joint position and sex on vastus medialis regional architecture