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The Runcorn area, north-west England, contains many pollution sources, the health effects of which have been under discussion for over 100 years. Preliminary investigations revealed an excess risk of mortality from kidney disease in people living nearest to several point sources of pollution, using distance as a proxy for exposure. Ongoing epidemiological investigations into the effect of ambient mercury exposure on dose and renal effect required a more refined assessment of exposure.

Assessment of exposure to mercury from industrial emissions: comparing "distance as a proxy" and dispersion modelling approaches