Open AccessPhenotypic heterogeneity of amyotrophic lateral sclerosis: a population based study
Author(s) -
Adriano Chiò,
Andrea Calvo,
Cristina Moglia,
Letizia Mazzini,
Gabriele Mora,
PARALS study group
Publication year - 2011
Publication title -
journal of neurology neurosurgery and psychiatry
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 3.391
H-Index - 206
eISSN - 1468-330X
pISSN - 0022-3050
DOI - 10.1136/jnnp.2010.235952
Subject(s) - amyotrophic lateral sclerosis , phenotype , incidence (geometry) , epidemiology , population , medicine , upper motor neuron , biology , disease , genetics , optics , gene , environmental health , physics
Different amyotrophic lateral sclerosis (ALS) phenotypes have been recognised, marked by a varying involvement of spinal and bulbar upper and lower motor neurons. However, the differential characteristics of these phenotypes are still largely unknown.
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