English (United Kingdom)

https://curated-unify.zendy.io/wp-json/zendy-region/v1/featured_content/oa?rat=en

https://curated-unify.zendy.io/wp-json/zendy-region/v1/highlighted_journal/

Global: Zendy Plus annual

Presents the access of premium content as premium feature

Premium Content

Presents the keyphrase highlighting as premium feature

Keyphrase Highlighting

Presents the summarisation as premium feature

Summarisation

Insights

Presents the pdf analysis as premium feature

PDF Analysis

Presents the zaia usage as premium feature

ZAIA

Global: Zendy Tools annual

Global: Zendy Free Plan

Global: Zendy Tools monthly

Global: Zendy Plus monthly

Case Reports Case 1. A 17-year-old girl with the chief complaint of difficulty in walking. She was the product of an uneventful pregnancy and normal delivery at full term. She sat at 1 year but did not start to walk until the age of 4. From the start walking appeared awkward and she fell frequently, but she progressed slowly and when seen she could still walk quite easily without assistance. The patient had no complaints about her hands but on examination some changes were noted; other systems appeared normal. She had completed the 6th grade at school and had beeii an average scholar. Physical examination showed a well-developed and well-nourished girl of average intelligence, with normal speech. Abnormalities were confined to the nervous system. The cranial nerves were intact: in particular the fundi were normal and there was no nystagmus. In the motor system no wasting was noted, but there was some hypotonia in the extremities. Grip was somewhat weak on both sides, and movements at the ankles were weak; otherwise no motor deficit was present. Co-ordination was good. All the tendon reflexes were absent. The abdominal superficial reflexes were also absent and the plantar responses were flexor. Touch sensation was lost in the hands up to the mid-forearm and in the lower extremities up to the knees. Pinprick and temperature sensations were diminished to the wrists and to the middle of the thighs. Vibration sense was lost up to the elbows in the upper limbs and up to the iliac crest in both lower limbs. Position sense was also impaired in the fingers and toss. Deep pain sensibility and stereognosis were intact. Romberg's sign was present and walking was ataxic; she could not keep to a straight line Nerve trunks were not enlarged on palpation. There was no deformity of the feet. Investigations showed a normal chest x-ray, a 2-hour post-prandial blood sugar of 100 mg./100 ml. Blood urea nitrogen of 11 mg./100 ml., haemoglobin 14-7 g./ 100 ml., haematocrit 45%, and white blood cell count of 5200, with a normal differential. Urine and stool examination showed no abnormalities. Venereal

A recessively inherited mixed polyneuropathy of early onset.