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To measure the childhood and life course socioeconomic exposures of people born between 1871 and 1949, and then to estimate the probability of death between 1965 and 1994, the probability of functional limitation in 1994, and the combined probability of dying or experiencing functional limitation during this period. SETTING, PARTICIPANTS AND DESIGN: Data were from the Alameda County Study (California) and pertained to people aged 17-94 years (n = 6,627) in 1965 (baseline). Socioeconomic position (SEP) in childhood was based on respondent's reports of their father's occupation, and life course disadvantage was measured by cross-classifying childhood SEP and the respondent's education and household income in 1965. The health outcomes were all-cause mortality (n = 2,420) and functional limitation measured using the Nagi index (n = 453, 17.4% of those alive in 1994). Relationships were examined before and after adjustment for changed socioeconomic circumstances after 1965.

journal of epidemiology and community health

Socioeconomic disadvantage in childhood and across the life course and all-cause mortality and physical function in adulthood: evidence from the Alameda County Study