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patients who underwent LPS (n= 84) and LPT (n= 44) for apparent early-stage BOTs from 2004 to 2019. Seventy (54.68%) have been treated with radical surgery and 58 (45.32%) with fertility-sparing (FS) treatment. Factors associated with recurrence were investigated. Disease-free survival curves were compared with Kaplan-Meier analysis. Results When comparing LPS vs. LPT, median age at surgery was 45.5 vs. 59 (p <0.001). With a median of follow up of 84.7 months (range:2.7–348.8), 14 patients (10.94%) recurred: 10/14 (64.28%) and 4/14 (28.57%) had ovarian and peritoneal relapse, respectively. Only 3/14 of the recurred patients had malignant transformation (21.45%). Factors such as surgical approach (LPS vs. LPT), histotype and extra ovarian surgery did not impact on recurrence (pvalues=NS). Conservative treatment (vs. radical surgery) was associated with recurrence (p=0.01) and unfavorable 5-year DFS (Log-Rank = 0.01), while no impact of the surgical approach on DFS was found (LPS vs. LPT; Log-Rank =0.32). Conclusions Patients who underwent FS surgery for BOTs had higher risk of recurrence and unfavorable disease-free survival compared to those who had radical treatment, while surgical approach did not negatively impact on survival. A strict follow-up should be recommended for early detection of potential recurrences.

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116 Analysis of histopathological features, molecular results and serum tumour markers in cases of fallopian tube involvement by metastatic gastrointestinal adenocarcinoma