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Clostridium difficile mediates intestinal inflammation by releasing toxin A (TxA), a potent enterotoxin. Cathelicidins (Camp as gene name, LL-37 peptide in humans and mCRAMP peptide in mice) are antibacterial peptides that also posses anti-inflammatory properties.

The antimicrobial peptide cathelicidin modulatesClostridium difficile-associated colitis and toxin A-mediated enteritis in mice