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Lynch syndrome is caused by germline mismatch repair (MMR) gene mutations. The PREMM(1,2,6) model predicts the likelihood of a MMR gene mutation based on personal and family cancer history.

Comparison of the clinical prediction model PREMM<sub>1,2,6</sub>and molecular testing for the systematic identification of Lynch syndrome in colorectal cancer

Comparison of the clinical prediction model PREMM1,2,6and molecular testing for the systematic identification of Lynch syndrome in colorectal cancer

Comparison of the clinical prediction model PREMM_1,2,6and molecular testing for the systematic identification of Lynch syndrome in colorectal cancer