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Smith and Nolan’s overview of central venous catheters (CVCs) states that evidence from 56 trials shows that antiseptic or antimicrobial impregnation of CVCs reduces the risk of bloodstream infection related to their use.1 2 The dilemma for clinicians, however, is which types of impregnation work best and for whom.The best available evidence on the type of impregnation comes from a network meta-analysis combining direct and indirect comparisons.3 …

Impregnated central venous catheters should be readily used to reduce risk of bloodstream infection