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Topography of neuron loss in the retinal ganglion cell layer in human glaucoma
Author(s) -
Yunlong Lei,
N.J. Garrahan,
B. Hermann,
Michael P. Fautsch,
D H Johnson,
M. Rosario Hernandez,
Michael E. Boulton,
James P. Morgan
Publication year - 2009
Publication title -
british journal of ophthalmology
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 2.016
H-Index - 153
eISSN - 1468-2079
pISSN - 0007-1161
DOI - 10.1136/bjo.2009.159210
Subject(s) - retinal ganglion cell , retinal , glaucoma , retina , ganglion , biology , ganglion cell layer , population , ophthalmology , optic disk , anatomy , medicine , neuroscience , environmental health
To determine if retinal ganglion cell (RGC) loss influences the loss of surrounding RGCs to generate clustered patterns of cell death in human glaucoma. It is hypothesised that retinal ganglion cell loss accelerates the loss of surrounding cells to generate, at a local, cellular scale, clustered patterns of retinal of RGC death. The absence of these interactions would result in a diffuse pattern RGC loss.

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