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s or anecdotal studies of rituximab Disease Author(s) No. of patients Rheumatoid arthritis Cohen et al. 520 Emery et al. 465 Strand et al. 161 Edwards et al 161 Popa et al. 37 Higashida et al. 17 Moore et al. 10 Kneitz et al. 5 Leandro et al. 22 De Vita et al. 5 Scheinberg et al. 10 Maher et al. 1 Cambridge et al. 15 Leandro et al. 24 Roll et al. 17 Microscopic polyangiitis, Stasi et al. 10 Eriksson et al. 9 Microscopic polyangiitis, Churg-Strauss syndrome Smith et al. 11 Wegener’s granulomatosis Aries et al. 8 Keogh et al. 10 Sanchez-Cano et al. 1 Tektonidou et al. 1 Bachmeyer et al. 1 Ferraro et al. 1 Kallenbach et al. 1 Memet et al. 1 Specks et al. 1 ANCA vasculitis Clatworthy et al. 1 Churg-Strauss syndrome Koukoulaki et al. 2 Kaushik et al. 1 Cryoglobulinaemia Type II and III Sansonno et al. 20 CryoglobulinaemiaType II. Quartuccio et al. 5 Cryoglobulinaemia Type III Basse et al. 7 Cryoglobulinaemia hepatitis C virus Cai et al. 1 Cryoglobulinaemia Type II hepatitis C virus Pekow et al. 3 Cryoglobulinemia Type I non-Hodgkin’s lymphoma Telander et al. 1 Cryoglobulinaemia Type II Bryce et al. 8 Zaja et al. 15 Arzoo et al. 1 Basse et al. 3 Ghijsels et al. 1 Koukoulaki et al. 1 Lamprecht et al. 1 Zaja et al. 15 Bryce et al. 11 Cryoglobulinaemia Type I Nehme et al. 2 Sjögren’s syndrome Ring et al. 1 Touma et al. 1 Pijpe et al. 15 Pijpe et al. 1 Voulgarelis et al. 6 Voulgarelis et al. 4 Gottenberg et al. 6 Ahmadi-Simab et al. 1 Harner et al. 1 Somer et al. 1 Shih et al. 1 Ramos-Casals et al. 2 Juvenile idiopathic arthritis polyarticular Kuek et al. 1 Juvenile idiopathic arthritis with EBV-associated lymphoproliferative disorder (LPD) Kelaidi et al. 1 Disease Author(s) No. of patients Systemic lupus erythematosus Armstrong et al. 1 Gormond-Mennesson et al. 26 Haddad et al. 11 Jansson et al. 2 Kotani et al. 1 MacDermott et al. 7 Marks, Tullus et al. 7 Ng et al. 7 Rech et al. 1 Risselada et al. 2 Smith et al. 11 Tokunaga et al. 10 Leandro et al. 502 24 Anolik et al., Looney et al. 17 Tokunga et al. 5 Ng et al. 24 Elderbauer et al. 1 SLE Carroll et al. 4 Jacobson et al. 1 Vigna et al 22 Antiphospholipid syndrome Ahn et al. 1 Ames et al. 1 Trappe et al. 1 Veneri et al. 1 Antiphospholipid syndrome and catastrophic antiphospholipd antibody syndrome Rubenstein et al. 3 Myopathy Arlet et al. 2 Antisynthetase syndrome Brulhart et al. 1 Dermatomyositis Dinh et al. 3 Lambotte et al. 1 Chung et al. 8 Levine et al. 7 Dermatomyositis and polymyositis Noss et al. 3 Chiappetta et al. 1 Still’s disease Ahnadi et al. 2 APPENDIX 3: ABSTRACTS OR ANECDOTAL STUDIES OF RITUXIMAB Continued iii22 Furst, Breedveld, Kalden, et al

Updated consensus statement on biological agents for the treatment of rheumatic diseases, 2007