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N-methyl-D-aspartate receptor (NMDAR) activation and downstream transduction pathways are crucial for pain signalling. Fibromyalgia (FM) is a common pain syndrome of unclear aetiology that is often drug-refractory but may benefit from treatment with electroacupuncture (EA). We examined the contributions of NMDAR signalling to FM pain and EA responses in a mouse model.

Effects of Electroacupuncture in a Mouse Model of Fibromyalgia: Role of N-Methyl-D-Aspartate Receptors and Related Mechanisms