Open AccessInterplay between Peptidoglycan Biology and Virulence in Gram-Negative Pathogens
Author(s) -
Carlos Juan,
Gabriel Torrens,
Isabel M. Barceló,
Antonio Oliver
Publication year - 2018
Publication title -
microbiology and molecular biology reviews
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 6.358
H-Index - 247
eISSN - 1098-5557
pISSN - 1092-2172
DOI - 10.1128/mmbr.00033-18
Subject(s) - biology , peptidoglycan , virulence , microbiology and biotechnology , gram , gram negative bacteria , bacterial protein , bacteria , genetics , gene , escherichia coli
The clinical and epidemiological threat of the growing antimicrobial resistance in Gram-negative pathogens, particularly for β-lactams, the most frequently used and relevant antibiotics, urges research to find new therapeutic weapons to combat the infections caused by these microorganisms. An essential previous step in the development of these therapeutic solutions is to identify their potential targets in the biology of the pathogen.
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