Open AccessTgIF2K-B Is an eIF2α Kinase in Toxoplasma gondii That Responds to Oxidative Stress and Optimizes Pathogenicity
Author(s) -
Leonardo Augusto,
Jennifer Martynowicz,
Parth H. Amin,
Kenneth Carlson,
Ronald C. Wek,
William J. Sullivan
Publication year - 2021
Publication title -
mbio
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 3.562
H-Index - 121
eISSN - 2161-2129
pISSN - 2150-7511
DOI - 10.1128/mbio.03160-20
Subject(s) - toxoplasma gondii , clearance , biology , immune system , pathogenicity , oxidative stress , population , virology , microbiology and biotechnology , parasite hosting , immunology , antibody , medicine , biochemistry , world wide web , urology , environmental health , computer science
Toxoplasma gondii is a single-celled parasite that infects nucleated cells of warm-blooded vertebrates, including one-third of the human population. The parasites are not cleared by the immune response and persist in the host by converting into a latent tissue cyst form.
Accelerating Research
Robert Robinson Avenue,
Oxford Science Park, Oxford
OX4 4GP, United Kingdom
Address
John Eccles HouseRobert Robinson Avenue,
Oxford Science Park, Oxford
OX4 4GP, United Kingdom