English (United Kingdom)

https://curated-unify.zendy.io/wp-json/zendy-region/v1/featured_content/oa?rat=en

https://curated-unify.zendy.io/wp-json/zendy-region/v1/highlighted_journal/

Global: Zendy Plus annual

Presents the access of premium content as premium feature

Premium Content

Presents the keyphrase highlighting as premium feature

Keyphrase Highlighting

Presents the summarisation as premium feature

Summarisation

Insights

Presents the pdf analysis as premium feature

PDF Analysis

Presents the zaia usage as premium feature

ZAIA

Global: Zendy Tools annual

Global: Zendy Free Plan

Global: Zendy Tools monthly

Global: Zendy Plus monthly

The gist of the letter by Friaes et al. (1) seems to be that an emerged clone of emm 89 Streptococcus pyogenes documented in three peer-reviewed publications (2–4) to be present in the United Kingdom, United States, Iceland, and Finland also may be present in Portugal. This conclusion was reached by analysis of publicly available full-genome sequence data for >900 emm 89 strains and comparisons performed with very limited genetic information (data from multilocus sequence type characterization, PCR analysis of the hasABC region, and DNA sequencing of the nga gene and its promoter region) for 95 Portuguese emm 89 strains. These Portuguese strains appear to be a convenience sample, rather than population based, an investigative approach that has led to erroneous conclusions, as described in previous studies (4). Unfortunately, the validity of the speculative claim by Friaes et al. (1) cannot be appropriately evaluated for at least three reasons. First, full-genome sequencing of the strains recovered from Portuguese patients was not conducted, which means that genomic relationships among the Portuguese and previously studied strains …

mbio

Musser et al. Reply to “Emergence of the Same Successful Clade among Distinct Populations of <i>emm</i> 89 Streptococcus pyogenes in Multiple Geographic Regions”

Musser et al. Reply to “Emergence of the Same Successful Clade among Distinct Populations of emm 89 Streptococcus pyogenes in Multiple Geographic Regions”