Open AccessHost Susceptibility to endogenous viruses: defective, glycoprotein-expressing proviruses interfere with infections
Author(s) -
Harriet L. Robinson,
Susan M. Astrin,
A Senior,
Felix H. Salazar
Publication year - 1981
Publication title -
journal of virology
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 2.617
H-Index - 292
eISSN - 1070-6321
pISSN - 0022-538X
DOI - 10.1128/jvi.40.3.745-751.1981
Subject(s) - biology , glycoprotein , virology , virus , endogenous retrovirus , viral envelope , endogeny , membrane glycoproteins , microbiology and biotechnology , genetics , genome , gene , endocrinology
Three defective endogenous avian leukosis viruses, ev3, ev6 and ev9, interfered with subgroup E virus infections, ev3, ev6, and ev9 expressed high levels of subgroup E envelope glycoproteins. These glycoproteins reduced the activity of cellular receptors for subgroup E viruses. ev3 and ev6 protected chickens and cultured cells from subgroup E virus infections.
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