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Superinfection ofEscherichia coli with amber mutants of R17 phage which produce R17 replicase inhibits production of the RNA phage Qβ, the DNA phage fd, and the host enzyme β-galactosidase. Inhibition required R17 replicase production and was related to the amount of replicase produced.

R17 Bacteriophage Replicase: Association with the Inhibition of Qβ, fd Bacteriophage and β-Galactosidase Production