Complete Genome Sequence of a Porcine Epidemic Diarrhea Virus Variant
Author(s) -
Jianfei Chen,
Xiaozhen Liu,
Da Shi,
Hongyan Shi,
Xin Zhang,
Li Feng
Publication year - 2012
Publication title -
journal of virology
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 2.617
H-Index - 292
eISSN - 1070-6321
pISSN - 0022-538X
DOI - 10.1128/jvi.07150-11
Subject(s) - biology , virology , sequence (biology) , genome , whole genome sequencing , virus , genetics , diarrhea , computational biology , gene , medicine
In 2011, outbreaks of viral diarrhea were observed on most swine-breeding farms in most of the provinces of China. The disease is characterized by vomiting, severe diarrhea, and a high mortality rate (82.3%) in newborn piglets. The clinical appearance was similar to that of porcine epidemic diarrhea virus (PEDV) infection. PEDVs were detected in samples (feces or small intestines) from most farms. In order to investigate whether there is a PEDV variant circulating in China, we sequenced and analyzed the complete genome of the recently identified field strain, CH/FJND-3/2011. The sequence data indicate that this PEDV variant prevails in China.
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