Open AccessComplete Genome Sequence of the Bacteriophage YMC01/01/P52 PAE BP, Which Causes Lysis of Verona Integron-Encoded Metallo-β-Lactamase-Producing, Carbapenem-Resistant Pseudomonas aeruginosa
Author(s) -
Jongsoo Jeon,
Jae-won Kim,
Dongeun Yong,
Kyungwon Lee,
Yunsop Chong
Publication year - 2012
Publication title -
journal of virology
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 2.617
H-Index - 292
eISSN - 1070-6321
pISSN - 0022-538X
DOI - 10.1128/jvi.02730-12
Subject(s) - biology , podoviridae , lytic cycle , bacteriophage , pseudomonas aeruginosa , integron , genome , microbiology and biotechnology , whole genome sequencing , myoviridae , lysogenic cycle , genetics , dna , plasmid , gene , escherichia coli , bacteria , virus
Multidrug-resistant Pseudomonas aeruginosa commonly causes serious nosocomial infections. In this study, a novel lytic bacteriophage belonging to a member of the family Podoviridae, YMC01/01/P52 PAE BP, which infects carbapenem-resistant Pseudomonas aeruginosa, was isolated and characterized. YMC01/01/P52 PAE BP genome was analyzed by whole-genome sequencing and putative function identification. The bacteriophage genome consists of a double-stranded linear DNA genome of 49,381 bp with a GC content of 62.16%.
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