Open AccessComplete Genome Sequence of a Coxsackievirus B3 Isolated from a Sichuan Snub-Nosed Monkey
Author(s) -
Wenqi He,
Huijun Lu,
Kui Zhao,
Deguang Song,
Xianying Gai,
Feng Gao
Publication year - 2012
Publication title -
journal of virology
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 2.617
H-Index - 292
eISSN - 1070-6321
pISSN - 0022-538X
DOI - 10.1128/jvi.02365-12
Subject(s) - biology , sequence (biology) , genome , virology , whole genome sequencing , coxsackievirus , genetics , computational biology , virus , enterovirus , gene
Coxsackievirus B3 (CVB3) is an enterovirus in the family Picornaviridae that is significant to human health, being associated with myocarditis, aseptic meningitis, and pancreatitis, among other conditions. In addition to humans, Sichuan snub-nosed monkeys can be infected and killed by CVB3. Here, we report the first complete genome sequence of a novel coxsackievirus B3 strain, SSM-CVB3, which was isolated from a deceased Sichuan snub-nosed monkey with severe myocarditis. Our findings may aid in understanding the evolutionary characteristics and molecular pathogenesis of this virus.
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