Open AccessDifferential Effect of Deleting Members of African Swine Fever Virus Multigene Families 360 and 505 from the Genotype II Georgia 2007/1 Isolate on Virus Replication, Virulence, and Induction of Protection
Author(s) -
Anusyah Rathakrishnan,
Samuel Connell,
Vlad Petrovan,
Katy Moffat,
Lynnette C. Goatley,
Tamara Jabbar,
P.J. Sánchez-Cordón,
Ana Luísa Reis,
Linda K. Dixon
Publication year - 2022
Publication title -
journal of virology
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 2.617
H-Index - 292
eISSN - 1070-6321
pISSN - 0022-538X
DOI - 10.1128/jvi.01899-21
Subject(s) - biology , virulence , virology , virus , viral replication , genotype , gene , attenuated vaccine , immunization , genetics , antibody
African swine fever has a high socioeconomic impact and no vaccines to aid control. The African swine fever virus (ASFV) has many genes that inhibit the host’s interferon response.