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The Complete Genome Sequence of Bacteriophage CP21 Reveals Modular Shuffling in Campylobacter Group II Phages
Author(s) -
Jens A. Hammerl,
Claudia Jäckel,
Jochen Reetz,
Stefan Hertwig
Publication year - 2012
Publication title -
journal of virology
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 2.617
H-Index - 292
eISSN - 1070-6321
pISSN - 0022-538X
DOI - 10.1128/jvi.01252-12
Subject(s) - biology , shuffling , genome , genetics , bacteriophage , sequence (biology) , campylobacter , whole genome sequencing , dna , computational biology , gene , bacteria , escherichia coli , programming language , computer science
Campylobacter group II phages described so far share a high degree of sequence similarity. We report the 182,833-bp genomic sequence of the closely related group II phage CP21 and show that it has a completely different genomic organization. As in other group II phages, the CP21 genome is composed of large modules separated by long DNA repeat regions which obviously trigger recombination and modular shuffling.

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