Complete Genome Sequence of an Overattenuated Highly Pathogenic Porcine Reproductive and Respiratory Syndrome Virus | Zendy

Jiajun Wu | Zendy; Nanhua Chen | Zendy; Wei Han | Zendy; Zhen Cao | Zendy; Xiaoyu Deng | Zendy; Lilin Wang | Zendy; Xiuling Yu | Zendy; Zhi Zhou | Zendy; Xiangdong Li | Zendy; Jishu Shi | Zendy; Kegong Tian | Zendy

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Complete Genome Sequence of an Overattenuated Highly Pathogenic Porcine Reproductive and Respiratory Syndrome Virus

Author(s) -

Jiajun Wu,

Nanhua Chen,

Wei Han,

Zhen Cao,

Xiaoyu Deng,

Lilin Wang,

Xiuling Yu,

Zhi Zhou,

Xiangdong Li,

Jishu Shi,

Kegong Tian

Publication year - 2012

Publication title -

journal of virology

Language(s) - English

Resource type - Journals

SCImago Journal Rank - 2.617

H-Index - 292

eISSN - 1070-6321

pISSN - 0022-538X

DOI - 10.1128/jvi.00710-12

Subject(s) - porcine reproductive and respiratory syndrome virus , biology , virology , virus , genome , sequence (biology) , whole genome sequencing , gene , genetics

JXA1-P170 is an overattenuated highly pathogenic porcine reproductive and respiratory syndrome virus (HP-PRRSV) that has been passaged in vitro 170 times. Vaccination with JXA1-P170 cannot protect pigs against JXA1 challenge. Compared with the parental virus JXA1, JXA1-P170 contains 1 nucleotide (nt) deletion and 113 nt mutations leading to 59 amino acid substitutions. Here we announce the first complete genome sequence of the overattenuated HP-PRRSV.

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